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What is 4-Methylpropiophenone CAS No: 5337-93-9

November 23, 2022

   4-methylpropiophenone is an aromatic ketone that is propiophenone bearing a methyl group at C-4. It derives from a propiophenone.

   CAS No: 5337-93-9

   Formula: C10H12O

   Synonyms:1-Propanone,1-(4-methylphenyl)-;Propiophenone,4′-methyl-;1-(4-Methylphenyl)-1-propanone;4′-Methylpropiophenone;p-Methylpropiophenone;Ethyl p-tolyl ketone;Ethyl 4-methylphenyl ketone;1-(4-Tolyl)-1-propanone;NSC 852;1-p-Tolylpropan-1-one

   China Export:From 2018.11 to 2019.11, total export volume of 4′-Methylpropiophenone from China was 17,340,007KG while total export value was $118,432,361. The biggest proportion of exporting volume in the last 12 months was 11.42% in 2019.03.

   Categories:Pharmaceutical Intermediates  >  Analgesics

                                                                  4-Methylpropiophenone CAS 5337-93-9

   4′-Methylpropiophenone is a chemical reagent used in electrocarboxylation reactions. 4′-Methylpropiophenone can be used as a building block to synthesize. N-(4-Chlorophenyl)-N′-[1-(4-methylphenyl)propyl]urea as a potential CRAC channel inhibitor.

Mono and trinuclear cobaloxime/organocobaloxime complexes, which are used as efficient catalysts for the synthesis of cyclic carbonates. Tolperisone (TOL) via acid-catalyzed reaction with piperidine hydrochloride and 1,2-dioxolane.

   4-Methylpropiophenone is a chemical reagent with an aromatic ketone that is propiophenone bearing a methyl group at C-4. It serves as pharmaceutical and synthesis material intermediate, and it is also used in electrocarboxylation reactions.

   4'-methylpropiophenone has been reported to be used in the synthesis of pharmaceutical compounds such as tolperisone and other muscle relaxants. The substance is also a starting material in the synthesis of 4-methylmethcathinone (mephedrone). Mephedrone has been encountered as a ‘legal high’ and on the illicit drug market masquerading as cocaine (in powder form), MDMA (in tablet form) and as an adulterant. According to the 2016 European Drugs Market Report produced by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA), mephedrone has created a specific demand and carved its own distinct market share.

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